Mark D. Bevan

This study shows that movement-related increases in subthalamic nucleus activity enhance locomotion in mice, with specific effects observed in disease models.

This study identifies early dysregulation in the basal ganglia indirect pathway in Q175 HD mice before cell loss, showing hypoactivity in striatal neurons and hyperactivity in GPe neurons.

The paper investigates abnormal network dynamics in the GPe-STN circuit of Parkinsonian mice and identifies key changes in neuronal activity and connectivity.