Author

Sarah J. Briston

University of ManchesterORCID 0000-0001-9772-2007Unclaimed ORCID profile · follow to get notified of new preprints

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Signature Assays, Organisms & Methods

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Assay:electrophysiology· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1

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Andrew W. TraffordiD· 1 shared David A. EisneriD· 1 shared Katharine M. DibbiD· 1 shared Luigi A. VenetucciiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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4 top collaborators · 6 mutual co-author links

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1 shared paperPhysiology

Andrew W. TraffordORCID

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1 paper

Recent·Most cited

Increased calcium spark frequency and variability of action potential duration precede early after depolarisations in isolated ventricular myocytes

Sarah J. Briston, David A. Eisner, Katharine M. Dibb, Luigi A. Venetucci, Andrew W. Trafford

This study shows that increased action potential duration variability and calcium sparks precede early afterdepolarisations in ventricular myocytes, suggesting calcium handling instability as a key mechanism for drug-induced arrhythmias.

bioRxiv · May 10, 2026 · PreprintPhysiology