Author

David A. Eisner

University of ManchesterORCID 0000-0002-7002-3748Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:electrophysiology· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1

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Andrew W. TraffordiD· 1 shared Katharine M. DibbiD· 1 shared Luigi A. VenetucciiD· 1 shared Sarah J. BristoniD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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4 top collaborators · 6 mutual co-author links

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1 shared paperPhysiology

Andrew W. TraffordORCID

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1 paper

Recent·Most cited

Increased calcium spark frequency and variability of action potential duration precede early after depolarisations in isolated ventricular myocytes

Sarah J. Briston, David A. Eisner, Katharine M. Dibb, Luigi A. Venetucci, Andrew W. Trafford

This study shows that increased action potential duration variability and calcium sparks precede early afterdepolarisations in ventricular myocytes, suggesting calcium handling instability as a key mechanism for drug-induced arrhythmias.

bioRxiv · May 10, 2026 · PreprintPhysiology