David B. Mark Welch

Hyperosmotic Stress of HL-60/S4 Cells: Gene Set Enrichment Analysis and Microscopy Changes

This study examines the effects of hyperosmotic stress on HL-60/S4 cells using transcript abundance and microscopy, revealing changes in chromatin structure, gene expression, and cellular processes.

Phenotypic Changes in Undifferentiated and Retinoic Acid Differentiated HL-60/S4 Cells with-or-without LBR Knockdown

This study uses GSEA to examine how LBR knockdown affects differentiation and phenotypic differences in HL-60 cell lines, finding changes in heterochromatin, ribosome proteins, and nucleolar structure.

The Effects of Lamin B Receptor knockdown on a Myeloid Leukemia Cell

This study investigates the effects of Lamin B Receptor knockdown on the transcriptome and morphology of HL-60/S4 cells, identifying changes in Golgi and ribosome-related genes and nucleolar structure.

The Multifaceted Phenotype of Senescent HL-60/S4 Macrophages

The paper uses GSEA to analyze the transcriptome of HL-60/S4 macrophages, identifying senescence-related gene sets and phenotypic changes.

Development of Highly Efficient CRISPR-Mediated Gene Editing in the Rotifer Brachionus manjavacas

The paper develops a CRISPR-mediated gene editing protocol in rotifers, demonstrating efficient knockout and knockin mutations in key genes.