Donald E. Olins

This paper describes the formation of Envelope-Limited Chromatin Sheets (ELCS) in HL-60/S4 cells treated with retinoic acid, showing their structural and biochemical characteristics and comparing them to phorbol ester-induced macrophages.

This study examines how nuclear pore complex structure and function change under different cellular stresses in HL-60/S4 cells using GSEA.

This study examines the effects of hyperosmotic stress on HL-60/S4 cells using transcript abundance and microscopy, revealing changes in chromatin structure, gene expression, and cellular processes.

This study uses GSEA to examine how LBR knockdown affects differentiation and phenotypic differences in HL-60 cell lines, finding changes in heterochromatin, ribosome proteins, and nucleolar structure.

This study investigates the effects of Lamin B Receptor knockdown on the transcriptome and morphology of HL-60/S4 cells, identifying changes in Golgi and ribosome-related genes and nucleolar structure.

The paper uses GSEA to analyze the transcriptome of HL-60/S4 macrophages, identifying senescence-related gene sets and phenotypic changes.

The paper maps DNA methylation changes during differentiation of HL-60/S4 cells, showing enhancer and CTCF site methylation drives transcriptional reprogramming.

This study shows TNF-α induces different cell cycle gene responses in promyelocytic and granulocytic HL-60/S4 cells, with promyelocytes showing upregulation and granulocytes downregulation, and granulocytes shifting towards a macrophage-like transcriptome.

The paper uses Hi-C and RNA-seq to identify and compare structural variants in HL-60 and HL-60/S4 cell lines, finding novel SVs and differences in their stability.

The paper shows that neutrophil migration through small pores disrupts inactive chromatin organization, as revealed by transcriptomic and Hi-C analyses.