Fanxin Long

This study shows that impaired glycolysis in bone tissue of aged mice leads to reduced bone formation, and that enhancing glycolysis can improve bone mass.

The paper defines murine bone marrow mesenchymal and stromal cell progenitor identities and temporal emergence using a single cell atlas from fetal life to 18 months.

The paper identifies Adipoq+ stromal cells in bone marrow as a source of IGF-1 that promotes endocortical bone formation in mature female mice without affecting trabecular bone or hematopoiesis.

This study identifies Gli1+ cells as a progenitor population in meniscus development and injury repair, showing their therapeutic potential in preventing osteoarthritis.