Ling Qin

The paper identifies common differentially regulated microRNAs in skeletal aging and radiation-induced bone deterioration, linking them to WNT pathway modulation and senescence.

This study investigates how synovial microenvironment stiffness changes during OA progression and how it affects fibroblast and macrophage behavior through mechanosignaling and cell-cell interactions.

This paper identifies Prg4+ fibro-adipogenic progenitors in muscle as critical for bone fracture repair by transforming into bone cells and promoting healing.

This study maps human bone marrow niches using single-cell transcriptomics and proteomic imaging, identifying distinct cellular environments and their roles in hematopoiesis and AML.

This study shows YAP and TAZ regulate osteoblast precursor mobilization and angiogenesis during bone development, linking mechanical cues to vascular and bone formation.

The paper evaluates a scalable approach using scRNA-seq to generate cell-type specific transcriptomic profiles of mesenchymal lineage cells from mouse bone marrow-derived stromal cells.

This study shows IFT20 regulates mesenchymal stem cell fate by controlling TGF-β-Smad2/3-Glut1 signaling and glucose metabolism, preventing adipocyte differentiation.

This study shows that Rcn3 regulates collagen modification and fibrillogenesis in postnatal tendon development, affecting tendon structure and mechanical properties.

This study identifies Gli1+ cells as a progenitor population in meniscus development and injury repair, showing their therapeutic potential in preventing osteoarthritis.

This study shows YAP and TAZ promote periosteal osteoblast precursor expansion and differentiation to accelerate bone fracture healing.