Pietro Pinoli

This paper identifies statins as having anticancer effects through synthetic lethality, validated in vitro on breast, ovarian, and cervical cancer cell lines.

The paper evaluates 23 imputation models for cross-cell type epigenomic data, finding quality assessment challenging due to distributional shifts, data availability, and redundant metrics.

The paper enhances Non-Negative Matrix Tri-Factorization to predict antitumor drug sensitivity by integrating data types and testing on a CCLE dataset.

The paper describes a biobanking initiative collecting genetic and clinical data from over 1,000 SARS-CoV-2-positive individuals to study multi-organ involvement and genetic factors in COVID-19 severity.

The paper proposes a post-Mendelian genetic model integrating common and rare variants to predict severe vs. mild COVID-19 outcomes in an Italian cohort.

ViruSurf is a database that integrates viral sequences and metadata from multiple sources, enabling complex searches to support research on viral sequences and their variants.

The paper introduces the Viral Conceptual Model (VCM) to organize and query virus sequence data, demonstrating its utility with SARS-CoV-2 and linking it to host phenotype data.