Author

Chang Zhou

The University of TokyoORCID 0000-0001-9796-9966Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Chang Zhou3 papers · Biomanufacturing Center, Department of Mechanical Engineering, Tsinghua University, Haidian District, Beijing 100084, China;

Biology Disciplines

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Biochemistry· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Organism:Arabidopsis· 2 Research Focus:chromatin & epigenetic regulation· 2 Assay:DNA methylation· 2 Approach:experimental assay· 2 Approach:biophysical modeling· 1 Research Focus:gene regulatory network inference· 1 Research Focus:protein folding & dynamics· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Alejandro Peñafiel-AyalaiD· 2 shared Daniel B. SloaniD· 2 shared Luis Gabriel BriebaiD· 2 shared Shin‐ichi ArimuraiD· 2 shared Chuande WangiD· 1 shared Noe Baruch‐TorresiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

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6 top collaborators · 14 mutual co-author links

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2 shared papersBiochemistry

Alejandro Peñafiel-AyalaORCID

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2 papers

Recent·Most cited

BiochemistrybioRxivPreprintAug 21, 2026

Plant MutS Homolog 1 is a mismatch-directed nuclease required for organelle genome maintenance

Alejandro Peñafiel-Ayala, Chang Zhou, Noe Baruch‐Torres…·Luis Gabriel Brieba

This study identifies AtMsh1 as a mismatch-directed nuclease in Arabidopsis that facilitates DNA repair in organelles, reducing mutation rates.

2 citations

ArabidopsisDNA methylation

𝕏 PostBluesky

Plant BiologybioRxivPreprintJun 11, 2026

Uracil/guanine mismatches trigger MutS HOMOLOG1-dependent mitochondrial DNA double-strand breaks in Arabidopsis

Chang Zhou, Alejandro Peñafiel-Ayala, Chuande Wang…·Shin‐ichi Arimura

This study shows that MSH1 promotes DNA double-strand breaks in Arabidopsis mitochondria triggered by uracil/guanine mismatches, supporting its role in maintaining genome integrity.

1 citation

ArabidopsisDNA methylation

𝕏 PostBluesky