Luis Gabriel Brieba

This study reconstructs the plant organellar homologous recombination pathway in Arabidopsis, showing that AtRecA1-mediated recombination is enhanced by plant-specific ssDNA-binding proteins, while AtRecA2 and AtRecA3 require these proteins for activity.

This study identifies AtMsh1 as a mismatch-directed nuclease in Arabidopsis that facilitates DNA repair in organelles, reducing mutation rates.

This paper identifies separate metal-binding sites in Pol γ that regulate its DNA synthesis and strand displacement activities, revealing structural and biochemical mechanisms for mitochondrial DNA replication.

This study shows that Arabidopsis thaliana organellar DNA polymerases can bypass UV-induced [6-4] photoproducts, with activity dependent on specific amino acid insertions and Mn²⁺.

This study shows that MSH1 promotes DNA double-strand breaks in Arabidopsis mitochondria triggered by uracil/guanine mismatches, supporting its role in maintaining genome integrity.

This study investigates the expansion of the MutS gene family in plants, identifying origins through gene duplication, endosymbiotic gene transfer, and horizontal gene transfer, and highlights their roles in organelle genetics.

This study identifies and functionally characterizes the Lin28/let-7 circuit in axolotl regeneration, showing its role in metabolic reprogramming during limb regeneration.