Eric Villard

CardioShift resolves cell-to-cell functional heterogeneity in hiPSC-derived cardiomyocytes by accounting for nested variance, revealing hidden subpopulations and condition-dependent phenotypes.

This study identifies 80 genetic loci and 61 effector genes associated with dilated cardiomyopathy through GWAS and integrates transcriptomic data to uncover biological pathways and cellular states involved in the disease.

This study shows that CASK depletion improves intercalated disc organization and ventricular function in multiple models, suggesting CASK as a repressor of ID structure and function in cardiac disease.

This study performs a large GWAS on dilated cardiomyopathy, identifying two new loci and confirming two existing ones, with potential therapeutic implications.