ImmunologybioRxivPreprint
Immune and Mutational Profile of Gene-Edited Low-Immunogenic Human Primary Cholangiocyte Organoids
Sandra Petrus-Reurer, Adrian Baez‐Ortega, Winnie Lei…·Kourosh Saeb‐Parsy
This study generates HLA-edited cholangiocyte organoids with reduced immunogenicity and reports their mutation profiles and immune response in vitro and in vivo.
DOI 10.1101/2025.01.20.628680