Author

Adebowale Adeniran

Yale UniversityORCID 0000-0001-9820-632XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Genetics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 2 Approach:statistical model· 2 Research Focus:variant effect prediction· 2 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Assay:whole-exome sequencing· 1

Frequent Co-Authors

Arya ManiiD· 2 shared Andrew JuiD· 1 shared Arnar GeirssoniD· 1 shared Arpita Neogi· 1 shared Brisa Paliuqi· 1 shared Dipanjan BanerjeeiD· 1 shared Fatemehsadat EsteghamatiD· 1 shared Guanghao Ge· 1 shared

Activity by Year

2018-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersGenetics

Arya ManiORCID

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3 papers

Recent·Most cited

GeneticsbioRxivPreprintSep 26, 2026

Variant-Specific Rewiring of Lysosomal Positioning by STARD9 Produces Opposite Cholesterol Trafficking Outcomes

Mehdi Dianatpour, Dipanjan Banerjee, HyunKyung Kim…·Arya Mani

The paper identifies STARD9 as a causal gene for dyslipidemias and atherosclerosis, showing how its variants alter lysosomal positioning and cholesterol trafficking with opposing effects on HDL and triglycerides.

DOI 10.64898/2026.09.25.754437

humanmouse

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Cancer BiologybioRxivPreprintOct 8, 2025

Deconvolving mutation and selection reveals stage-specific drivers of thyroid cancer

Moein Rajaei, Andrew Ju, Adebowale Adeniran, Jeffrey P. Townsend

This study quantifies cancer-driving mutations in thyroid cancer stages by analyzing selection pressures, revealing stage-specific drivers of tumorigenesis and metastasis.

DOI 10.1101/2025.10.08.681166

humanwhole-exome sequencing

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Molecular BiologybioRxivPreprintAug 22, 2018

TCF7L2 Regulation of GATA6-dependent and -Independent Vascular Smooth Muscle Cell Plasticity and Intimal Hyperplasia

Roshni Srivastava, Harshvardhan Rolyan, Yi Xie…·Arya Mani

This study shows TCF7L2 promotes VSMC differentiation and inhibits proliferation, reducing intimal hyperplasia in mice with LRP6 mutations.

DOI 10.1101/397851

mouseexperimental assay

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