TCF7L2 Regulation of GATA6-dependent and -Independent Vascular Smooth Muscle Cell Plasticity and Intimal Hyperplasia
Roshni Srivastava, Harshvardhan Rolyan, Yi Xie, Na Li, Neha Bhat, Lingjuan Hong, Fatemehsadat Esteghamat, Adebowale Adeniran, Arnar Geirsson, Jiasheng Zhang, Guanghao Ge, Marcelo A. Nóbrega, Kathleen A. Martin, Arya Mani
This study shows TCF7L2 promotes VSMC differentiation and inhibits proliferation, reducing intimal hyperplasia in mice with LRP6 mutations.
bioRxiv · Aug 22, 2018 · PreprintMolecular Biology