David H. Hilko

This study identifies Plasmodium aspartyl-tRNA synthetase as an antimalarial target by showing how natural products inhibit protein translation through reaction hijacking.

The paper introduces DNADetect™ probes as an EdU alternative for DNA labeling in mammalian cells, bypassing thymidine kinase dependency and demonstrating efficient DNA incorporation.

This paper identifies two drug-like fragments that bind to a cryptic pocket in B. pseudomallei DsbA, showing weak binding but potential for optimization.