Author

Yuao Zhu

Pfizer (United States)ORCID 0000-0001-9831-6836Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Genomics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:drug response / drug discovery· 1 Organism:human· 1 Approach:machine learning (classical)· 1 Organism:mouse· 1 Approach:statistical model· 1 Research Focus:variant calling· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Hao LiiD· 2 shared Rhonda D. CardiniD· 2 shared Aijia Yu· 1 shared Alexey V. GribenkoiD· 1 shared Alpha A. LeeiD· 1 shared Amanda BalesanoiD· 1 shared Amin Behzadi· 1 shared Amit S.S. KalgutkariD· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersMicrobiology

Hao LiORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

MicrobiologyScience AdvancesPeer-reviewedAug 30, 2024

Discovery of SARS-CoV-2 papain-like protease (PLpro) inhibitors with efficacy in a murine infection model

Michelle R. Garnsey, Matthew C. Robinson, Luong T. Nguyen…·Alpha A. Lee

This study identifies potent SARS-CoV-2 PLpro inhibitors using machine learning, showing efficacy in a mouse model of COVID-19.

77 citationstop 1%

mousemachine learning (classical)

𝕏 PostBluesky

GenomicsbioRxivPreprintMar 29, 2022

Genetic surveillance of SARS-CoV-2 Mpro reveals high sequence and structural conservation prior to the introduction of protease inhibitor Paxlovid

Jonathan T. Lee, Qingyi Yang, Alexey V. Gribenko…·Hao Li

This study analyzes SARS-CoV-2 Mpro sequences from 4.89 million genomes to assess mutation patterns and structural conservation before Paxlovid use, finding rare escape mutations and strong purifying selection.

6 citations

humanwhole-genome sequencing

𝕏 PostBluesky