Author

Alexey V. Gribenko

Pfizer (United States)ORCID 0000-0002-4285-4608Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:E. coli· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:protein structure· 1 Approach:statistical model· 1 Research Focus:variant calling· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Annaliesa S. AndersoniD· 2 shared Alexandre Esadze· 1 shared Arthur Illenberger· 1 shared Bradley Scott PerriniD· 1 shared Christopher Ponce· 1 shared David R. Keeney· 1 shared Hao LiiD· 1 shared Huixian WuiD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersMicrobiology

Annaliesa S. AndersonORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Structure-Based Design of a Highly Immunogenic, Conformationally Stabilized FimH Antigen for a Urinary Tract Infection Vaccine

Natalie C. Silmon de Monerri, Ye Che, Joshua A. Lees, J. Jasti, Huixian Wu, Matthew C. Griffor, Srinivas Kodali, Julio Cesar Hawkins, Jacqueline Lypowy, Christopher Ponce, Kieran Curley, Alexandre Esadze, Juan Guillermo Cárcamo, Thomas McLellan, David R. Keeney, , Robert G. K. Donald

The paper designs a conformationally stabilized FimH antigen for a UTI vaccine, showing improved immunogenicity and structural similarity to native FimH.

PLoS Pathogens · Feb 19, 2025Peer-reviewedMicrobiology

Genetic surveillance of SARS-CoV-2 Mpro reveals high sequence and structural conservation prior to the introduction of protease inhibitor Paxlovid

Jonathan T. Lee, Qingyi Yang, Alexey V. Gribenko, Bradley Scott Perrin, Yuao Zhu, Rhonda D. Cardin, Paul Liberator, Annaliesa S. Anderson, Hao Li

This study analyzes SARS-CoV-2 Mpro sequences from 4.89 million genomes to assess mutation patterns and structural conservation before Paxlovid use, finding rare escape mutations and strong purifying selection.

bioRxiv · Mar 29, 2022 · PreprintGenomics