Author

Charan Thej

Temple UniversityORCID 0000-0001-9844-9735Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1

Frequent Co-Authors

Carolina GonzáleziD· 2 shared Cindy BenedictiD· 2 shared Darukeshwara JoladarashiiD· 2 shared Maria CiminiiD· 2 shared Vandana MallaredyiD· 2 shared Ajit MagadumiD· 1 shared Amit Kumar Rai· 1 shared Andrew D. ChesneyiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersImmunology

Carolina GonzálezORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Podoplanin Positive Cell-derived Extracellular Vesicles Contribute to Cardiac Amyloidosis After Myocardial Infarction

Maria Cimini, Ulrich H. E. Hansmann, Carolina González, Andrew D. Chesney, May M. Truongcao, Erhe Gao, Tao Wang, Rajika Roy, Elvira Forte, Vandana Mallaredy, Charan Thej, Ajit Magadum, Darukeshwara Joladarashi, Cindy Benedict, Water J. Koch, , Raj Kishore

This study identifies that Podoplanin-expressing mesenchymal stromal cells release exosomes that trigger SAA3 overproduction in macrophages, leading to cardiac amyloidosis after myocardial infarction.

Cell Reports · Mar 1, 2025Peer-reviewedImmunology

Circular RNA Circ-Cdr1as modulates Macrophage phenotype and Cardiac Reparative Function by Circ-Cdr1as-miR-7-Klf4 pathway

Carolina González, Maria Cimini, Vandana Mallaredy, Cindy Benedict, Darukeshwara Joladarashi, Charan Thej, Zhongjian A Cheng, May Trungcao, Amit Kumar Rai, Venkata Naga Srikanth Garikipati, Raj Kishore

This study shows circ-Cdr1as modulates macrophage phenotype and cardiac repair via the circ-Cdr1as-miR-7-Klf4 pathway, improving cardiac function post-myocardial infarction.

bioRxiv · Feb 21, 2025 · PreprintCell Biology