Author

Carlos Lopez-Garcia

Cancer Research UKORCID 0000-0001-9848-8216Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Research Focus:benchmarking· 1 Research Focus:database / resource· 1 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

Caroline DiveiD· 2 shared Julia OgdeniD· 2 shared Alastair R. W. KerriD· 1 shared Anshuman ChaturvediiD· 1 shared Anthony OojageeriD· 1 shared Arman HossainiD· 1 shared Jennifer BeaneiD· 1 shared Matthew G. RobertsiD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersCancer Biology

Caroline DiveORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintAug 28, 2025

Studying a human genetic model of lung squamous cell carcinoma with organotypic cultures and xenografts uncovers distinct advantages of each system and implicates NOTCH1 loss in tumour development

Julia Ogden, Robert Sellers, Anthony Oojageer…·Carlos Lopez-Garcia

The paper compares organotypic cultures and xenografts of a human lung squamous cell carcinoma model, finding that xenografts better reflect tumor gene expression and reveal NOTCH1 loss as a driver.

DOI 10.1101/2025.08.28.672595

humanbulk RNA-seq

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BioinformaticseLifePeer-reviewedMar 9, 2023

Interrogating the Precancerous Evolution of Pathway Dysfunction in Lung Squamous Cell Carcinoma Using XTABLE

Matthew G. Roberts, Julia Ogden, Arman Hossain…·Carlos Lopez-Garcia

The paper introduces XTABLE, an open-source tool for analyzing PML transcriptomic data, and uses it to study chromosomal instability as a biomarker for LUSC progression and pathway onset.

8 citations

humanbulk RNA-seq

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