PathologybioRxivPreprint
Myeloperoxidase promotes fibrosis by inhibiting cathepsin K to bias the lung toward ECM accumulation
Patrick A. Link, Jack H. Wellmerling, Jeffrey A. Meridew…·Daniel J. Tschumperlin
This study identifies MPO as a post-translational inhibitor of CatK, linking acute inflammation to sustained fibrosis through impaired collagen degradation.