Author

Joanna Krakowiak

Whitehead Institute for Biomedical ResearchORCID 0000-0001-9873-0746Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Systems Biology· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Organism:yeast· 2 Assay:bulk RNA-seq· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Assay:Hi-C· 1

Frequent Co-Authors

David PincusiD· 2 shared Ahmad S. KhaliliD· 1 shared Ali Beyzavi BiD· 1 shared Chuangye Qi· 1 shared Feng Xiong· 1 shared Hana El‐SamadiD· 1 shared Holger K. EltzschigiD· 1 shared Jieun KimiD· 1 shared

Activity by Year

2018-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersSystems Biology

David PincusORCID

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3 papers

Recent·Most cited

SARS-CoV-2 Restructures the Host Chromatin Architecture

Ruoyu Wang, Joo‐Hyung Lee, Feng Xiong, Jieun Kim, Lana Al Hasani, Xiaoyi Yuan, Pooja Shivshankar, Joanna Krakowiak, Chuangye Qi, Yanyu Wang, Holger K. Eltzschig, Wenbo Li

This study investigates how SARS-CoV-2 alters host chromatin architecture and epigenome, revealing disruptions in 3D genome structure and transcriptional regulation of immune-related genes.

bioRxiv · Jul 20, 2021 · PreprintMolecular Biology

A dataset to explore kinase control of environmental stress responsive transcription

Kieran Mace, Joanna Krakowiak, Hana El‐Samad, David Pincus

The paper presents a dataset analyzing kinase activity and gene expression in yeast under environmental stress, revealing how kinases modulate stress responses.

bioRxiv · Feb 12, 2019 · PreprintSystems Biology

Hsf1 phosphorylation generates cell-to-cell variation in Hsp90 levels and promotes phenotypic plasticity

Xu Zheng, Ali Beyzavi B, Joanna Krakowiak, Nikit Patel, Ahmad S. Khalil, David Pincus

The paper shows that Hsf1 phosphorylation creates cell-to-cell variation in Hsp90 levels, which enhances phenotypic plasticity in budding yeast.

Cell Reports · Mar 1, 2018Peer-reviewedSystems Biology