MicrobiologybioRxivPreprint
YY1 Binding Motif Upstream of Rep/Cap Increases AAV Yield and Full Capsids
Yuri Ofusa, Sanae Nishio, Tatsuji Enoki…·Kenji Ohba
This study shows that inserting the YY1 binding motif upstream of the Rep/Cap gene increases AAV vector yield and improves the empty/full capsid ratio without affecting infectivity.
DOI 10.64898/2026.05.21.726733