Author

Jean‐Christophe Jonas

UCLouvainORCID 0000-0001-9882-5438Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:gene regulatory network inference· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Agnieszka LatosińskaiD· 1 shared Ane Olazagoitia‐GarmendiaiD· 1 shared Antonia VlahouiD· 1 shared Bruno J. Santacreu· 1 shared Cristina CosentinoiD· 1 shared Cristina Moreno‐CastroiD· 1 shared David CommuniiD· 1 shared Harald MischakiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperGenetic & Genomic Medicine

Agnieszka LatosińskaORCID

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2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintJul 23, 2026

TRMT10A deficiency and tRNA fragmentation disrupt human pancreatic β-cell identity and insulin maturation

Cristina Moreno‐Castro, María Nicol Arroyo, Khadija Benabdallah…·Mariana Igoillo‐Esteve

This study shows TRMT10A deficiency causes β-cell dysfunction by promoting tRNA fragmentation and disrupting PCSK1 expression, leading to impaired insulin maturation and glucose-stimulated insulin secretion.

DOI 10.64898/2026.07.22.739528

humanbulk RNA-seq

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Genetic & Genomic MedicinemedRxivPreprintOct 7, 2025

Pan-fibrotic gene expression signature in major chronic diseases by integrative bulk and single-cell transcriptomic analyses

Mayra Alejandra Jaimes Campos, Rafael Stroggilos, Joost Peter Schanstra…·Agnieszka Latosińska

The paper identifies a conserved pan-fibrotic gene expression signature across liver, kidney, and heart fibrosis using bulk and single-cell transcriptomic data.

2 citations

humanbulk RNA-seq

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