GenomicsbioRxivPreprint
Atrial fibrillation associated common risk variants in SYNE2 lead to lower expression of nesprin-2α1 and increased nuclear stiffness
Nana Liu, Jeffrey Hsu, Gautam Mahajan…·Jonathan D. Smith
This study identifies AF-associated SNPs in SYNE2 that reduce SYNE21 expression and increase nuclear stiffness, potentially contributing to AF pathogenesis.
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