Author

Kang Chen

National Institutes of HealthORCID 0000-0001-9892-3118Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Allen-Dexter Saliganan· 1 shared Andrea CeruttiiD· 1 shared Annamari RankiiD· 1 shared Ashok S. BhagwatiD· 1 shared Bao Q. VuongiD· 1 shared Bashar Mohamad· 1 shared Bihui HuangiD· 1 shared Bo Pei· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperMolecular Biology

Allen-Dexter Saliganan

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintJan 10, 2024

A Germinal Center Checkpoint of AIRE in B Cells Limits Antibody Diversification

Jordan Zhou, Bo Pei, Guang Wen Sun…·Kang Chen

This study identifies AIRE as a checkpoint in germinal center B cells that limits antibody diversification by inhibiting AID function, leading to autoimmunity and impaired immune responses.

1 citation

mousebulk RNA-seq

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Molecular BiologybioRxivPreprintNov 30, 2022

Detection of IL23p40 via Positron Emission Tomography Visualized Inflammatory Bowel Disease

Farzaneh Rezazadeh, Nicholas Ramos, Allen-Dexter Saliganan…·Nerissa T. Viola

This study demonstrates that immunoPET targeting IL23p40 can detect inflammation in a mouse model of IBD, offering a potential non-invasive diagnostic approach.

1 citation

mouseexperimental assay

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