Author

Allen Frederic Ryan

University of California San DiegoORCID 0000-0001-9894-8083Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2 Genetic & Genomic Medicine· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Research Focus:differential expression· 2 Organism:human· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Assay:electronic health records· 1 Approach:experimental assay· 1 Research Focus:GWAS / association mapping· 1

Frequent Co-Authors

Adam X. MaihoferiD· 1 shared Alicia G. SykesiD· 1 shared Ann Chi Yan WongiD· 1 shared Antonio De MaioiD· 1 shared Caroline E. Mackey· 1 shared Caroline M. NievergeltiD· 1 shared Chamini Jayamali PereraiD· 1 shared Dale R. Gerstmann· 1 shared

Activity by Year

2018-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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1 shared paperGenetic & Genomic Medicine

Adam X. MaihoferORCID

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4 papers

Recent·Most cited

Genetic & Genomic MedicinemedRxivPreprintFeb 28, 2025

Genome-wide association study meta-analysis brings monogenic hearing loss genes into the polygenic realm

Royce Ellen Clifford, Jacquelyn Johnson, Caroline E. Mackey…·Caroline M. Nievergelt

This paper conducts a GWAS meta-analysis of sensorineural hearing loss, identifying 108 loci, including 54 novel genes, and shows substantial genetic overlap between cohorts despite differing phenotypes.

1 citation

humanGWAS summary statistics

𝕏 PostBluesky

NeurosciencebioRxivPreprintNov 6, 2021

Association of cochlear outer hair cell - type II spiral ganglion afferents with protection from noise-induced hearing loss

Jennie M. E. Cederholm, Kristina E. Parley, Chamini Jayamali Perera…·Gary D. Housley

This study shows that OHC-type II spiral ganglion afferents are critical for MOC efferent-mediated protection against noise-induced hearing loss in mice.

DOI 10.1101/2021.11.06.467554

mouseelectronic health records

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Molecular BiologyBMC Medical GenomicsPeer-reviewedMay 24, 2021

AGE IS ASSOCIATED WITH INCREASED EXPRESSION OF PATTERN RECOGNITION RECEPTOR GENES AND ACE2, THE RECEPTOR FOR SARS-COV-2: IMPLICATIONS FOR THE EPIDEMIOLOGY OF COVID-19 DISEASE

Stephen W. Bickler, David M. Cauvi, Kathleen M Fisch…·Antonio De Maio

The paper investigates how age affects the expression of PRR genes and ACE2 in human dermal fibroblasts, linking increased expression to higher risk of severe COVID-19 outcomes.

18 citations

humanbulk RNA-seq

𝕏 PostBluesky

NeurosciencebioRxivPreprintOct 25, 2018

Altered protein quality control contributes to noise-induced hearing loss

Nopporn Jongkamonwiwat, Ann Chi Yan Wong, Miguel A. Ramirez…·Jeffrey N. Savas

The paper investigates how noise exposure alters the cochlear proteome in mice, identifying proteostasis responses and proteins involved in regeneration and mitochondrial dysfunction in noise-induced hearing loss.

DOI 10.1101/452698

mouseproteomics

𝕏 PostBluesky