Anthony S Findley

The paper identifies genetic variants that modify gene expression in response to caffeine in vascular endothelial cells and shows their potential role in cardiovascular disease.

The paper identifies gene-environment interactions in gene regulation across cell types and treatments, revealing many genes missed by GTEx.

The paper investigates gene-environment interactions in coronary artery disease by analyzing RNA-seq and ATAC-seq data from endothelial cells exposed to environmental factors, finding links between environmental responses and CAD risk.

The paper shows gut microbiota influences host gene regulation, identifying specific taxa and genes, and demonstrates microbiome manipulation can alter gene expression profiles.

circuitSNPs predicts the functional effects of genetic variants on chromatin accessibility using a neural network that models regulatory modules from DNase-seq footprints.

The paper shows environmental changes cause widespread shifts in RNA processing across multiple cell types and identifies trans factor regulation of these changes.