Palur Venkata Raghuvamsi

Ara h 2 and FcϵRIα binding elicit state-dependent allostery in IgE

This study investigates how Ara h 2 and FcϵRI binding affect IgE structural dynamics and allosteric communication, revealing conformational changes and shifts in communication pathways.

An Integrative Approach to Rational Engineering of Dengue Virus-Like Particles

This study uses multiscale modeling, lipidomics, and experiments to engineer stable and immunogenic dengue virus-like particles by modifying protein-lipid interactions.

N153-linked glycans on envelope protein protect orthoflaviviruses from antibody-mediated clearance

This study shows that N153-linked glycans on dengue virus envelope protein help evade antibody-mediated clearance, with implications for immune evasion in related flaviviruses.

Structural Insights into Immature Dengue Virus-Like Particles Revealed by Cryo-EM and Molecular Dynamics Simulations

This study presents the cryo-EM structure of immature dengue serotype 2 VLPs and uses MD simulations to reveal their maturation mechanism and lipid dependency.

Dengue virus 2 capsid protein chaperones strand displacement without altering the capsid-coding region hairpin element's structural functionality

This study investigates how DENV2C chaperone activity facilitates strand displacement during RNA rearrangement without altering the structural functionality of the cHP hairpin element.

Dengue virus strain 2 capsid protein switches the annealing pathway and reduces the intrinsic dynamics of the conserved 5' untranslated region

This study shows that DENV2C switches the annealing pathway and reduces the intrinsic dynamics of the 5UTR, aiding in RNA replication.