Désirée R. Seib

This paper introduces a novel operant conditioning task to measure motivation to exercise in rats and validates it using calorie restriction.

This study shows that maternal high-sucrose diet during pregnancy alters fetal brain steroid levels but not maternal or fetal blood steroids.

This study shows that maternal high-sucrose diet alters steroid levels in the mother, placenta, and fetus, potentially affecting offspring neuroendocrinology and behavior.

This study shows that inhibiting adult neurogenesis affects spatial learning differently in male and female rats under stressful conditions, with males showing slower learning and females faster learning in cold water.

The paper investigates the effects of androgen synthesis inhibition and gonadectomy on behavioural flexibility in male rats, finding that inhibition reduces perseverative errors in learning tasks.

This study shows that blocking hippocampal neurogenesis in rats reduces activation of the ventral dentate gyrus and causes aversion to delayed rewards.

The paper examines the development and morphology of adult-born neurons in rats, finding they mature over months and have distinct features compared to neonatally-born neurons, contributing to hippocampal plasticity into old age.

This study shows that adult neurogenesis enhances efficient, nonspecific search strategies in a spatial alternation water maze task, particularly when platform locations alternate.

This study shows that increasing adult neurogenesis in rats reduces activity in developmentally-born dentate granule neurons, supporting an inhibitory role for new neurons in hippocampal function.

This study shows that male and female rats without adult neurogenesis can still discriminate local and distal cues in spatial memory tasks.