Huub C. J. Hoefsloot

The paper models glucosinolate biosynthesis dynamics in Arabidopsis under biotic stress using a mechanistic ODE model constrained by gene expression and metabolite data.

AbSolution enables integrated analysis of sequence-derived features in immune repertoires across datasets and conditions.

The paper introduces a method combining simulated and real metabolomics data using tensor factorization to improve pattern discovery, showing better performance in males for BMI-related phenotypes.

This study evaluates CP models for analyzing postprandial metabolomics data through simulations, showing their effectiveness in revealing metabolic patterns and group differences.

The paper develops partial least squares regression models to predict human blood lipoprotein subfractions from 1H NMR spectra, achieving high accuracy in independent cohorts.