GeneticsEMBO Molecular MedicinePeer-reviewed
Resolving mechanisms of immune-mediated disease in primary CD4 T cells
Christophe Bourges, Abigail F. Groff, Oliver S. Burren…·James Christopher Lee
The paper identifies a causal variant in a super-enhancer that disrupts an NF-κB regulatory circuit, leading to T-cell activation in immune-mediated diseases.
47 citations