Author

Sylvain Marcellini

University of ConcepciónORCID 0000-0001-9986-2054Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Research Focus:gene regulatory network inference· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Felipe AguileraiD· 2 shared Héctor CastilloiD· 2 shared Amy Kugath· 1 shared Anastassia Rubilar-Fajardo· 1 shared Anguela Castro· 1 shared Bernard BilloudiD· 1 shared Carlos Muñoz‐MontecinosiD· 1 shared Catherine Anne BoisvertiD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersDevelopmental Biology

Felipe AguileraORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Zebrafish armc9 mutant reveals a link between ARM-Type fold domain loss, inflammation, and spinal curvature

Anastassia Rubilar-Fajardo, Carlos Muñoz‐Montecinos, Gustavo Esperguel-Toledo, Sofía Carrasco, Anguela Castro, Paloma Alvarado, Amy Kugath, Raul R. Araya-Secchi, Miguel L. Allende, Sylvain Marcellini, Marcelo González, Juan Roman, Sebastián Boltaña, Felipe Aguilera, Timothy K. Cooper, , Ricardo Fuentes

This study identifies a link between ARM-type fold domain loss in zebrafish Armc9, inflammation, and spinal curvature, suggesting a role in ciliary signaling and adolescent idiopathic scoliosis.

bioRxiv · Apr 2, 2025 · PreprintDevelopmental Biology

Analysis of a shark reveals ancient, Wnt dependent, habenular asymmetries in jawed vertebrates

Maxence Lanoizelet, Léo Michel, Ronan Lagadec, Hélène Mayeur, Lucile Guichard, Valentin Logeux, Dany Séverac, Kyle J. Martin, Christophe Klopp, Sylvain Marcellini, Héctor Castillo, Nicolas Pollet, Eva Candal, Mélanie Debiais‐Thibaud, Catherine Anne Boisvert, , Sylvie Mazan

This study identifies ancient Wnt-dependent habenular asymmetries in sharks, suggesting a conserved developmental mechanism across jawed vertebrates.

Nature Communications · Nov 25, 2024Peer-reviewedDevelopmental Biology

Architecture and evolutionary conservation of Xenopus tropicalis osteoblast-specific regulatory regions shed light on bone diseases and early skeletal evolution

Héctor Castillo, Francisco Godoy, Clément Gilbert, Felipe Aguilera, Salvatore Spicuglia, Sylvain Marcellini

The paper identifies osteoblast-specific regulatory regions in Xenopus tropicalis and shows their conservation with human enhancers, linking them to skeletal diseases and evolutionary origins of bone.

bioRxiv · Aug 30, 2023 · PreprintGenomics