The paper identifies genes and regulatory networks involved in shark tooth regeneration using RNAseq, highlighting the role of mycn in dental stem cell proliferation.

bioRxiv · Aug 26, 2025 · PreprintDevelopmental Biology

The sensory shark: high-quality morphological, genomic and transcriptomic data for the small spotted catshark Scyliorhinus canicula reveal the molecular bases of sensory organ evolution in jawed vertebrates

Hélène Mayeur, Jake Leyhr, John F. Mulley, Nicolas Leurs, Léo Michel, Kanika Sharma, Ronan Lagadec, Jean‐Marc Aury, Owen G. Osborne, Peter O. Mulhair, Julie Poulain, Sophie Mangenot, Daniel Mead, Michelle Smith, Craig H. Corton, , Mélanie Debiais‐Thibaud

This study integrates genomic, transcriptomic, and morphological data from the small-spotted catshark to uncover molecular mechanisms underlying sensory organ evolution in jawed vertebrates.

Molecular Biology and Evolution · Dec 1, 2024Peer-reviewedEvolutionary Biology

Analysis of a shark reveals ancient, Wnt dependent, habenular asymmetries in jawed vertebrates

Maxence Lanoizelet, Léo Michel, Ronan Lagadec, Hélène Mayeur, Lucile Guichard, Valentin Logeux, Dany Séverac, Kyle J. Martin, Christophe Klopp, Sylvain Marcellini, Héctor Castillo, Nicolas Pollet, Eva Candal, Mélanie Debiais‐Thibaud, Catherine Anne Boisvert, , Sylvie Mazan

This study identifies ancient Wnt-dependent habenular asymmetries in sharks, suggesting a conserved developmental mechanism across jawed vertebrates.

Nature Communications · Nov 25, 2024Peer-reviewedDevelopmental Biology