Unraveling mitotic protein networks by 3D multiplexed epitope drug screening
Lorenz Maier, Stefan M. Kallenberger, Katharina Jechow, Marcel Waschow, Roland Eils, Christian Conrad
This paper introduces 3D SPECS, a method to map spatial protein localization in 3D cell cultures and analyze mitotic protein networks, revealing novel insights into spindle fragility and chromatin stress.
Molecular Systems Biology · Aug 1, 2018Peer-reviewedSystems Biology