BiochemistryChemBioChemPeer-reviewed
Switching Metazoan Fatty Acid Synthase Between Reducing and Non-reducing Elongation Mode via Programming of the Ketoreductase Domain
Damian L. Ludig, André Herber, Martin Grininger
This study engineers metazoan fatty acid synthase to switch from reducing to non-reducing elongation mode by modifying the ketoreductase domain, producing pyrone intermediates.
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