Author

Robert M. Hoffman

University of California San DiegoORCID 0000-0002-0049-0041Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Byung Mo KangiD· 1 shared Hiroaki KimuraiD· 1 shared Hiroyuki Tsuchiya· 1 shared Katsuhiro HayashiiD· 1 shared Kentaro IgarashiiD· 1 shared KOHEI MIZUTA· 1 shared Michael BouvetiD· 1 shared Norio YamamotoiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Byung Mo KangORCID

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1 paper

Recent·Most cited

Human fibrosarcoma cells selected for very-high doxorubicin resistance, acquire trabectedin and eribulin cross-resistance, remain sensitive to recombinant methioninase, and have increased c-MYC expression

Sei Morinaga, Qinghong Han, KOHEI MIZUTA, Byung Mo Kang, Michael Bouvet, Norio Yamamoto, Katsuhiro Hayashi, Hiroaki Kimura, Shinji Miwa, Kentaro Igarashi, Takashi Higuchi, Hiroyuki Tsuchiya, Satoru Demura, Robert M. Hoffman

This study shows that doxorubicin-resistant fibrosarcoma cells are cross-resistant to trabectedin and eribulin but remain sensitive to recombinant methioninase, with increased c-MYC expression.

Frontiers in Oncology · Dec 8, 2025Peer-reviewedCancer Biology