Author

Michael Bouvet

University of California San DiegoORCID 0000-0002-0086-2159Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Byung Mo KangiD· 1 shared Christopher W. BenneriD· 1 shared Emma Mathilde Kurstjens· 1 shared Hiroaki KimuraiD· 1 shared Hiroyuki Tsuchiya· 1 shared Ivonne Lozano‐Pope· 1 shared Jonathan Matthew HernandeziD· 1 shared Katsuhiro HayashiiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

Byung Mo KangORCID

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2 papers

Recent·Most cited

Human fibrosarcoma cells selected for very-high doxorubicin resistance, acquire trabectedin and eribulin cross-resistance, remain sensitive to recombinant methioninase, and have increased c-MYC expression

Sei Morinaga, Qinghong Han, KOHEI MIZUTA, Byung Mo Kang, Michael Bouvet, Norio Yamamoto, Katsuhiro Hayashi, Hiroaki Kimura, Shinji Miwa, Kentaro Igarashi, Takashi Higuchi, Hiroyuki Tsuchiya, Satoru Demura, Robert M. Hoffman

This study shows that doxorubicin-resistant fibrosarcoma cells are cross-resistant to trabectedin and eribulin but remain sensitive to recombinant methioninase, with increased c-MYC expression.

Frontiers in Oncology · Dec 8, 2025Peer-reviewedCancer Biology

Gastric cancer treatment target identified from an accelerated Helicobacter-induced gastric cancer mouse model

Emma Mathilde Kurstjens, Kristin E. Cox, Prerna Bali, Siamak Amirfakhri, Jonathan Matthew Hernandez, Ivonne Lozano‐Pope, Christopher W. Benner, Michael Bouvet, Marygorret Obonyo

The paper identifies PSMB8 as a potential therapeutic target in gastric cancer and shows carfilzomib's efficacy in reducing tumor growth and inducing apoptosis in a mouse model.

bioRxiv · Jun 14, 2025 · PreprintCancer Biology