Author

Astrid Bethe

Freie Universität BerlinORCID 0000-0002-0064-3909Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:E. coli· 1 Approach:experimental assay· 1 Research Focus:GWAS / association mapping· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:metagenomics· 1 Approach:statistical model· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Amanda S. Fivian-Hughes· 1 shared Angelika FruthiD· 1 shared Anne-Kathrin Liebschner· 1 shared Birgit WaltheriD· 1 shared Boas C.L. van der PutteniD· 1 shared C Förster· 1 shared Charlotte Huber· 1 shared Christa EwersiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperGenomics

Amanda S. Fivian-Hughes

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Bridging disciplines towards wastewater-based surveillance of antimicrobial resistance: frequency, local dynamics, and genomic characteristics of carbapenemase-producing Klebsiella pneumoniae

Katharina A. Werner, Vladimir Bajić, Christian Blumenscheit, David Baum, Daniel Desirò, Somayyeh Sedaghatjoo, Jeanette Barthelmes, Anne-Kathrin Liebschner, C Förster, Stephan Fuchs, Silver Anthony Wolf, Astrid Bethe, M. Hölzer, Birgit Walther

This paper develops a workflow for detecting carbapenemase-producing Klebsiella pneumoniae in wastewater using wet-lab methods and genomics, finding high prevalence and specific genetic markers.

bioRxiv · Mar 2, 2026 · PreprintMicrobiology

Genome-wide association reveals host-specific genomic traits in Escherichia coli

Sumeet K. Tiwari, Boas C.L. van der Putten, Thilo M. Fuchs, Nguyen Vinh Trung, Martin Bootsma, Rik Oldenkamp, Roberto Marcello La Ragione, Sébastien Matamoros, Ngô Thị Hoa, Christian Berens, Joy Leng, Julio Álvarez, Marta Ferrandis-Vila, Jenny M. Ritchie, Angelika Fruth, , Constance Schultsz

This study identifies host-specific genetic determinants in E. coli using genome-wide association, revealing lineage-specific adaptations to human, cattle, chicken, and pig hosts.

BMC Biology · Apr 10, 2023Peer-reviewedGenomics