Asymmetry in catalysis by Thermotoga maritima membrane-bound pyrophosphatase demonstrated by a non-phosphorous allosteric inhibitor
Keni Vidilaseris, Alexandros Kiriazis, Ainoleena Turku, Ayman Khattab, Niklas G. Johansson, Teppo O. Leino, Paula S. Kiuru, Gustav Boije af Gennäs, Seppo Meri, Jari T. Yli‐Kauhaluoma, Henri Xhaard, Adrian Goldman
The paper demonstrates asymmetry in the catalytic cycle of membrane-bound pyrophosphatases using a non-phosphorous allosteric inhibitor bound to Thermotoga maritima enzyme.
Science Advances · May 3, 2019Peer-reviewedMolecular Biology