Jure Mur

The paper performs genome-wide association studies on 439 high-abundance serum proteins in 15,035 Scottish individuals, identifying 1,553 SNP signals and 13 putative causal protein-outcome associations.

This study identifies aging genes in human blood by integrating epigenetic and transcriptomic data, finding genes enriched for immune functions that better replicate across populations and link to aging outcomes.

The paper shows that imputing DNA methylation loci from epigenome-wide data provides stronger associations with smoking and age than directly measured CpGs.

The paper investigates the association between VKORC1 genetic variation and dementia risk, finding a link with vascular dementia but not general or Alzheimer dementia, and no effect of warfarin use on risk.

The paper examines DNA methylation at the APOE gene in blood samples to assess its association with cholesterol, cognition, and risks of Alzheimer’s and cardiovascular disease.