Charting Postnatal Heart Development Using In Vivo Single-Cell Functional Genomics
Haofei Wang, Yanhan Dong, Yiran Song, Marazzano Colon, Nicholas Yapundich, Shea N. Ricketts, Xingyan Liu, Gregory Farber, Yunzhe Qian, Qian Li, Jiandong Liu
The paper creates a temporal and spatial atlas of postnatal heart development using single-nucleus transcriptomics and spatial transcriptomics, identifying 21 novel regulators of cardiomyocyte maturation through a new method called PIP-seq.
bioRxiv · Mar 10, 2025 · PreprintDevelopmental Biology