ARL15 promotes inflammatory fibroblast activation and disease severity in rheumatoid arthritis: integrated transcriptomic and collagen-induced arthritis model analyses
Sujit Kashyap, Anuj Kumar, Manisha Saini, Kumari Vijaya, Sriram Kunnoth, Puneet Mahajan, Suman Kundu, Uma Kumar, Bittianda Kuttapa Thelma
This study identifies ARL15 as a pro-inflammatory driver of rheumatoid arthritis by integrating transcriptomic, single-cell, and in vivo analyses, showing its therapeutic potential through inhibition in a mouse model.
bioRxiv · Jul 1, 2026 · PreprintImmunology