Author

Mario Sanhueza

Universidad MayorORCID 0000-0002-0125-0154Unclaimed ORCID profile · follow to get notified of new preprints

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Neuroscience· 1

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Organism:Drosophila· 1 Approach:experimental assay· 1

Frequent Co-Authors

Felipe A. CourtiD· 1 shared Francisco Muñoz-CarvajaliD· 1 shared Nicole SanhuezaiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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3 top collaborators · 3 mutual co-author links

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1 shared paperNeuroscience

Felipe A. CourtORCID

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1 paper

Recent·Most cited

Age-dependent H3K9 trimethylation by dSetdb1 impairs mitochondrial UPR leading to degeneration of olfactory neurons and loss of olfactory function in Drosophila.

Francisco Muñoz-Carvajal, Nicole Sanhueza, Mario Sanhueza, Felipe A. Court

This study shows that age-dependent H3K9 trimethylation by dSetdb1 impairs UPRMT in Drosophila olfactory neurons, leading to neurodegeneration and loss of olfactory function, which can be reversed by dSetdb1 knockdown.

eLife · Mar 26, 2026Peer-reviewedNeuroscience