Pharmacology & ToxicologybioRxivPreprint
Development of a nanomedicine approach to improve the therapeutic index of bexarotene.
Siân Rizzo, Carola Pepe, Thibault Albert…·Elaine L. Ferguson
This study conjugates bexarotene to dextrin to improve its solubility and in vitro potency but finds it does not reduce lipid toxicity in vivo.
DOI 10.64898/2026.10.05.756654