Sébastien Wielgoss

CRISPR-Cas interference decays rapidly with distance from the leader sequence in a long array

The paper shows that CRISPR-Cas interference in Myxococcus xanthus declines rapidly with distance from the leader sequence, with only ~4% of spacers effective, contrasting with ~95% effectiveness in Vibrio cholerae.

Predator adaptation to single prey species yields positive specialization and multiple forms of diversification

This study shows that adaptation of bacterial predators to a single prey species leads to increased specialization and diversification in predation profiles.