Sophia Renauld

The paper presents the first densely reconstructed adult fruit fly connectome integrating the brain and ventral nerve cord, revealing distributed control circuits involving local and long-range neural connections.

This study shows that neuronal activity is essential for the development of touch receptors, as genetic disruption of Piezo2 and Nav1.6 leads to structural and functional defects in mechanosensory neurons.

The paper shows that mechanoreceptor synapses in the brainstem develop differently based on their proximity to glabrous skin, shaping the central representation of touch.