Author

Alexandra R. Magee

Howard Hughes Medical Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 4

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Organism:mouse· 4 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Brendan P. LehnertiD· 2 shared Celine SantiagoiD· 2 shared Christopher A. GuevaraiD· 2 shared David D. GintyiD· 2 shared Deanna L. BensoniD· 2 shared George W. HuntleyiD· 2 shared Nusrat Africawala· 2 shared Pamela Del ValleiD· 2 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersNeuroscience

Brendan P. LehnertORCID

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Author profile →

4 papers

Recent·Most cited

Activity-dependent development of the body's touch receptors

Celine Santiago, Julianna Siegrist, Nusrat Africawala, Annie Handler, Aniqa Tasnim, Rabia Anjum, Josef Turecek, Brendan P. Lehnert, Sophia Renauld, Jinheon Choi, Michael Nolan-Tamariz, Michael Iskols, Alexandra R. Magee, Suzanne Paradis, Nikhil Sharma, David D. Ginty

This study shows that neuronal activity is essential for the development of touch receptors, as genetic disruption of Piezo2 and Nav1.6 leads to structural and functional defects in mechanosensory neurons.

Neuron · May 16, 2025Peer-reviewedNeuroscience

Parkinson's LRRK2-G2019S risk gene mutation drives sex-specific behavioral and cellular adaptations to chronic variable stress

Christopher A. Guevara, Kumayl Alloo, Swati Gupta, Romario Thomas, Pamela Del Valle, Alexandra R. Magee, Deanna L. Benson, George W. Huntley

This study investigates how the LRRK2-G2019S mutation affects sex-specific anxiety-like behaviors and neural activity in response to chronic stress in mice.

Frontiers in Behavioral Neuroscience · Sep 12, 2024Peer-reviewedNeuroscience

Development of prefrontal corticostriatal connectivity in mice

Roxana Mesias, Yosif Zaki, Christopher A. Guevara, Lauren G. Friedman, Ayan Hussein, Karen Therrien, Alexandra R. Magee, Nikolaos Tzavaras, Pamela Del Valle, Mark G. Baxter, George W. Huntley, Deanna L. Benson

This study investigates the development of prefrontal corticostriatal connectivity in mice, showing that axons target their zones early and synapses do not undergo extensive pruning, with Cdh8 playing a role in behavioral outcomes.

iScience · Sep 22, 2023Peer-reviewedNeuroscience

Mechanoreceptor synapses in the brainstem shape the central representation of touch

Brendan P. Lehnert, Celine Santiago, Erica L. Huey, Alan J. Emanuel, Sophia Renauld, Nusrat Africawala, Ilayda Alkislar, Yang Zheng, Ling Bai, Charalampia Koutsioumpa, Jennifer T. Hong, Alexandra R. Magee, Christopher D. Harvey, David D. Ginty

The paper shows that mechanoreceptor synapses in the brainstem develop differently based on their proximity to glabrous skin, shaping the central representation of touch.

bioRxiv · Feb 2, 2021 · PreprintNeuroscience