Interferon lambda signaling to maternal dendritic cells protects against congenital Zika virus infection
Margaret R. Dedloff, Thomas R. Reinhardt, Tessa‐Jonne F. Ropp, Joel Rivera-Cardona, Celeste R. Robles, Rebecca L. Casazza, Jennifer Ashley Ezzell, Michelle S. Itano, Helen M. Lazear
This study shows that maternal IFN-lambda signaling to dendritic cells reduces transplacental ZIKV transmission in mice.
bioRxiv · Jan 27, 2026 · PreprintImmunology