Author

Donald Y.M. Leung

National Jewish HealthORCID 0000-0002-0177-3844Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Bioinformatics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:statistical model· 2 Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

Lianghua BiniD· 2 shared Akihiko UchiyamaiD· 1 shared Aleksandr B. StotlandiD· 1 shared Angel J. Keoseyan· 1 shared Brittany N. Richers· 1 shared Caroline Bronchick· 1 shared Cydney L. Rios· 1 shared Elena GolevaiD· 1 shared

Activity by Year

2018-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersMolecular Biology

Lianghua BinORCID

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3 papers

Recent·Most cited

Blood to Biomarker Quantitation in Under One Hour with Rapid Proteomics using a Hyperthermoacidic Protease

Steven M. Yannone, Vikas Tuteja, Olena Goleva, Donald Y.M. Leung, Aleksandr B. Stotland, Angel J. Keoseyan, Nathan G. Hendricks, Sarah J. Parker, Jennifer E. Van Eyk, Simion D. Kreimer

This paper develops a rapid proteomics method using HTA protease and LC-MS to quantify blood biomarkers in under an hour.

Analytical Chemistry · Mar 20, 2025Peer-reviewedBiochemistry

Atopic dermatitis complicated by recurrent eczema herpeticum is characterized by multiple, concurrent epidermal inflammatory endotypes

Nathan D. Jackson, Nathan T. Dyjack, Elena Goleva, Lianghua Bin, Michael T. Montgomery, Cydney L. Rios, Jamie L. Everman, Patricia A. Taylor, Caroline Bronchick, Brittany N. Richers, Donald Y.M. Leung, Max A. Seibold

This study identifies distinct epidermal inflammatory endotypes in atopic dermatitis patients with recurrent eczema herpeticum, showing concurrent type 2 cytokine, interferon, and IL-36γ-driven inflammation and dysregulated epidermal differentiation complex genes.

JID Innovations · Apr 1, 2024Peer-reviewedMolecular Biology

A data mining paradigm for identifying key factors in biological processes using gene expression data

Jin Li, Le Zheng, Akihiko Uchiyama, Lianghua Bin, Theodora M. Mauro, Peter M. Elias, Tadeusz Pawełczyk, Monika Sakowicz‐Burkiewicz, Magdalena Trzeciak, Donald Y.M. Leung, María I. Morasso, Peng Yu

This paper introduces a data mining paradigm to identify key factors in biological processes using gene expression data, demonstrating its effectiveness in epidermal development and cold-induced thermogenesis.

Scientific Reports · Jun 7, 2018Peer-reviewedBioinformatics