Author

Darren Chambers

National Institute for Health and Care ResearchORCID 0000-0002-0200-9274Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Francesco Muntoni AiD· 2 shared Alex Kavanagh· 1 shared Artadokht AghaeipouriD· 1 shared Benjamin W. JarvisiD· 1 shared Filipe NascimentoiD· 1 shared Francesco CatapanoiD· 1 shared Joanne NgiD· 1 shared Jyoti Dhar MalhotraiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersNeuroscience

Francesco Muntoni AORCID

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2 papers

Recent·Most cited

Neuronal targeted AAV Micro-Dystrophin restores neurobehavioural co-morbidities, grip strength and motor coordination in mdx52 mouse model of Duchenne Muscular Dystrophy

Konstantina Tetorou, Mónica Rebeca Gil-Garzon, Darren Chambers, Mustafa Görkem Özyurt, Filipe Nascimento, Wing Sum Chu, Simon N. Waddington, Benjamin W. Jarvis, Alex Kavanagh, Nicha Songsilph, Joanne Ng, Francesco Muntoni A

This study evaluates neuronal-targeted AAV micro-dystrophin therapy in mdx52 mice, showing IV delivery improves neurobehavioural, motor, and neuromuscular deficits more effectively than ICV delivery.

bioRxiv · May 26, 2026 · PreprintNeuroscience

A comprehensive spatiotemporal map of dystrophin isoform expression in the developing and adult human brain

Francesco Catapano, Reem R. Alkharji, Darren Chambers, Simran Singh, Artadokht Aghaeipour, Jyoti Dhar Malhotra, Patrizia Ferretti, Rahul Phadke, Francesco Muntoni A

This paper maps dystrophin isoform expression across human brain development and adulthood, revealing novel expression patterns in neurons and synapses.

Acta Neuropathologica Communications · May 21, 2025Peer-reviewedNeuroscience